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1

Langerin is a natural barrier to HIV-1 transmission by Langerhans cells

de Witte, Lot, Nabatov, Alexey, Pion, Marjorie, Fluitsma, Donna, de Jong, Marein A W P, de Gruijl, Tanja, Piguet, Vincent, van Kooyk, Yvette, Geijtenbeek, Teunis B H

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 295 KB

english, 2007

2

The ABC of dendritic cell development and function

Rieneke van de Ven, George L. Scheffer, Rik J. Scheper, Tanja D. de Gruijl

Journal:

Trends in Immunology

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

3

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

Santegoets, Saskia J. A. M., Dijkgraaf, Eveline M., Battaglia, Alessandra, Beckhove, Philipp, Britten, Cedrik M., Gallimore, Awen, Godkin, Andrew, Gouttefangeas, Cecile, de Gruijl, Tanja D., Koenen, H

Journal:

Cancer Immunology, Immunotherapy

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

4

Cross-talk between tumor and myeloid cells: how to tip the balance in favor of antitumor immunity

Lindenberg, Jelle J, Fehres, Cynthia M, van Cruijsen, Hester, Oosterhoff, Dinja, de Gruijl, Tanja D

Journal:

Year:

2011

Language:

english

File:

PDF, 968 KB

english, 2011

5

A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer

Wentink, Madelon Q, Broxterman, Henk J, Lam, Siu W, Boven, Epie, Walraven, Maudy, Griffioen, Arjan W, Pili, Roberto, van der Vliet, Hans J, de Gruijl, Tanja D, Verheul, Henk M W

Journal:

British Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 532 KB

english, 2016

6

Analysis of IgG reactivity against human papillomavirus type-16 E7 in patients with cervical intraepithelial neoplasm indicates an association with clearance of viral infection: results of a prospective study

Tanja D. de Gruijl, Hetty J. Bontkes, Jan M.M. Walboomers, Marij J. Stukart, Antoine A.J.P. Robbesom, B. Mary E. von Blomberg-van der Flier, Paul Herbrink, Ans J. Remmink, René H.M. Verheijen, Theo J.

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 913 KB

english, 1996

7

HPV 16 infection and progression of cervical intra-epithelial neoplasia: Analysis of HLA polymorphism and HPV 16 E6 sequence variants

Hetty J. Bontkes, Mark van Duin, Tanja D. de Gruijl, Maggie F. Duggan- Keen, Jan M. M. Walboomers, Marij J. Stukart, René H. M. Verheijen, Theo J. M. Helmerhorst, Chris J. L. M. Meijer, Rik J. Scheper

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 74 KB

english, 1998

8

Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia

Hetty J. Bontkes, Tanja D. de Gruijl, Adrie J.C. van den Muysenberg, René H.M. Verheijen, Marij J. Stukart, Chris J.L.M. Meijer, Rik J. Scheper, Simon N. Stacey, Margaret F. Duggan-Keen, Peter L. Ster

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

9

CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis

Krista Ouwehand, Saskia J. A. M. Santegoets, Derk P. Bruynzeel, Rik J. Scheper, Tanja D. de Gruijl, Susan Gibbs

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

10

Epidermis-to-dermis migration of immature Langerhans cells upon topical irritant exposure is dependent on CCL2 and CCL5

Krista Ouwehand, Rik J. Scheper, Tanja D. de Gruijl, Susan Gibbs

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

11

CD4+CD25hi regulatory T-cell frequency correlates with persistence of human papillomavirus type 16 and T helper cell responses in patients with cervical intraepithelial neoplasia

Johan W. Molling, Tanja D. de Gruijl, Judith Glim, Maria Moreno, Lawrence Rozendaal, Chris J.L.M. Meijer, Alfons J.M. van den Eertwegh, Rik J. Scheper, Mary E. von Blomberg, Hetty J. Bontkes

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 291 KB

english, 2007

12

Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression

Inge S. van Houdt, Berbel J.R. Sluijter, Laura M. Moesbergen, Wim M. Vos, Tanja D. de Gruijl, Barbara G. Molenkamp, Alfons J.M. van den Eertwegh, Erik Hooijberg, Paul A.M. van Leeuwen, Chris J.L.M. Me

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 296 KB

english, 2008

13

Unimpaired immune functions in the absence of Mrp4 (Abcc4)

Rieneke van de Ven, Jan de Groot, Anneke W. Reurs, Pepijn G.J.T.B. Wijnands, Koen van de Wetering, John D. Schuetz, Tanja D. de Gruijl, Rik J. Scheper, George L. Scheffer

Journal:

Immunology Letters

Year:

2009

Language:

english

File:

PDF, 709 KB

english, 2009

14

Serum-free generation of antigen presenting cells from acute myeloid leukaemic blasts for active specific immunisation

Ilse Houtenbos, Theresia M. Westers, Anita G. M. Stam, Tanja D. de Gruijl, Rik J. Scheper, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht

Journal:

Cancer Immunology, Immunotherapy

Year:

2003

Language:

english

File:

PDF, 328 KB

english, 2003

15

Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines

Tanja D. de Gruijl, Alfons J. M. van den Eertwegh, Herbert M. Pinedo, Rik J. Scheper

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 311 KB

english, 2008

16

Monophosphoryl lipid A plus IFNγ maturation of dendritic cells induces antigen-specific CD8+cytotoxic T cells with high cytolytic potential

Anja ten Brinke, Gijs van Schijndel, Remco Visser, Tanja D. de Gruijl, Jaap Jan Zwaginga, S. Marieke van Ham

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 640 KB

english, 2010

17

Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation

Willemijn van den Ancker, Marvin M. van Luijn, Jurjen M. Ruben, Theresia M. Westers, Hetty J. Bontkes, Gert J. Ossenkoppele, Tanja D. de Gruijl, Arjan A. van de Loosdrecht

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 555 KB

english, 2011

18

High susceptibility of c-KIT+CD34+precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model

Rieneke van de Ven, Sue Ellen Verbrugge, Anneke W. Reurs, Hetty J. Bontkes, Erik Hooijberg, Gerrit Jansen, Rik J. Scheper, George L. Scheffer, Tanja D. de Gruijl

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 441 KB

english, 2011

19

Exposure of CD34+precursors to cytostatic anthraquinone-derivatives induces rapid dendritic cell differentiation: implications for cancer immunotherapy

Rieneke van de Ven, Anneke W. Reurs, Pepijn G. J. T. B. Wijnands, Sandra van Wetering, Ada M. Kruisbeek, Erik Hooijberg, George L. Scheffer, Rik J. Scheper, Tanja D. de Gruijl

Journal:

Cancer Immunology, Immunotherapy

Year:

2012

Language:

english

File:

PDF, 610 KB

english, 2012

20

The novel bispecific diabody αCD40/αCD28 strengthens leukaemic dendritic cell-induced T-cell reactivity

Ilse Houtenbos, Saskia Santegoets, Theresia M. Westers, Quinten Waisfisz, Sergey Kipriyanov, Fedor Denkers, Rik J. Scheper, Tanja D. De Gruijl, Gert J. Ossenkoppele, Arjan A. Van De Loosdrecht

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

21

10.1038/13443

de Gruijl, Tanja D., Curiel, David T.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

22

CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic

Basav N. Hangalapura, Laura Timares, Dinja Oosterhoff, Rik J. Scheper, David T. Curiel, Tanja D. de Gruijl

Journal:

The Journal of Gene Medicine

Year:

2012

Language:

english

File:

PDF, 437 KB

english, 2012

23

Attenuation of invariant Natural Killer T-cell anergy induction through intradermal delivery of α-galactosylceramide

Hetty J. Bontkes, María Moreno, Basav Hangalapura, Jelle J. Lindenberg, Jan de Groot, Sinéad Lougheed, Hans J.J. van der Vliet, Alfons J.M. van den Eertwegh, Tanja D. de Gruijl, B. Mary E. von Blomber

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 970 KB

english, 2010

24

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection

Famke L. Schneiders, Rik J. Scheper, B. Mary E. von Blomberg, Andrea M. Woltman, Harry L.A. Janssen, Alfons J.M. van den Eertwegh, Henk M.W. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 624 KB

english, 2011

25

Activated iNKT cells promote Vγ9Vδ2-T cell anti-tumor effector functions through the production of TNF-α

Famke L. Schneiders, Renée C.G. de Bruin, Saskia J.A.M. Santegoets, Marc Bonneville, Emmanuel Scotet, Rik J. Scheper, Henk M.W. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet

Journal:

Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 514 KB

english, 2012

26

Feasibility of flowcytometric quantitation of immune effector cell subsets in the sentinel lymph node of the breast after cryopreservation

Kim M. van Pul, Ronald J.C.L.M. Vuylsteke, Herman Bril, Hein B.A.C. Stockmann, Tanja D. de Gruijl

Journal:

Journal of Immunological Methods

Year:

2012

Language:

english

File:

PDF, 559 KB

english, 2012

27

Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer

Charlotte M Huijts, Saskia J Santegoets, Alfons J van den Eertwegh, Laura S Pijpers, John B Haanen, Tanja D de Gruijl, Henk M Verheul, Hans J van der Vliet

Journal:

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

28

Tissue micro array analysis of gangliosideN-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

Hester van Cruijsen, Mariëlle Gallegos Ruiz, Paul van der Valk, Tanja D de Gruijl, Giuseppe Giaccone

Journal:

Year:

2009

Language:

english

File:

PDF, 3.14 MB

english, 2009

29

Circulating Vα24+Vβ11+ NKT cell numbers and dendritic cell CD1d expression in hepatitis C virus infected patients

Hans J.J. van der Vliet, Johan W. Molling, B. Mary E. von Blomberg, Wendy Kölgen, Anita G. Stam, Tanja D. de Gruijl, Chris J. Mulder, Harry L.A. Janssen, Nobusuke Nishi, Alfons J.M. van den Eertwegh,

Journal:

Clinical Immunology

Year:

2005

Language:

english

File:

PDF, 284 KB

english, 2005

30

Immunomodulation of the melanoma sentinel lymph node: A novel adjuvant therapeutic option

Barbara G. Molenkamp, Paul A.M. van Leeuwen, Alfons J.M. van den Eertwegh, Berbel J.R. Sluijter, Rik J. Scheper, Sybren Meijer, Tanja D. de Gruijl

Journal:

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

31

Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans cells

Krista Ouwehand, Sander W. Spiekstra, Judith Reinders, Rik J. Scheper, Tanja D. de Gruijl, Susan Gibbs

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 456 KB

english, 2010

32

A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo

Erin E. Thacker, Masaharu Nakayama, Bruce F. Smith, R. Curtis Bird, Zhanat Muminova, Theresa V. Strong, Laura Timares, Nikolay Korokhov, Ann Marie O’Neill, Tanja D. de Gruijl, Joel N. Glasgow, Kenzabu

Journal:

Year:

2009

Language:

english

File:

PDF, 766 KB

english, 2009

33

Matched Skin and Sentinel Lymph Node Samples of Melanoma Patients Reveal Exclusive Migration of Mature Dendritic Cells

Barbara G. Molenkamp, Ronald J.C.L.M. Vuylsteke, Paul A.M. van Leeuwen, Sybren Meijer, Wim Vos, Pepijn G.J.T.B. Wijnands, Rik J. Scheper, Tanja D. de Gruijl

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 547 KB

english, 2005

34

Sampling Tumor-Draining Lymph Nodes for Phenotypic and Functional Analysis of Dendritic Cells and T Cells

Ronald J.C.L.M. Vuylsteke, Paul A.M. van Leeuwen, Sybren Meijer, Pepijn G.J.T.B. Wijnands, Markwin G. Statius Muller, Dirk H. Busch, Rik J. Scheper, Tanja D. de Gruijl

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 514 KB

english, 2002

35

CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation

Joana G. Brandão, Rik J. Scheper, Sinéad M. Lougheed, David T. Curiel, Bryan W. Tillman, Winald R. Gerritsen, Alfons J.M. van den Eertwegh, Herbert M. Pinedo, Hidde J. Haisma, Tanja D. de Gruijl

Journal:

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

36

Fondation Rene Touraine Pour La Dermatologie

Tanja D. de Gruijl, Florent Ginhoux, Philippe Bousso, Thomas Bieber, Vincent Piguet, Esther von Stebut, Diana Dudziak, Ronjon Chakraverty

Journal:

Experimental Dermatology

Year:

2012

Language:

english

File:

PDF, 281 KB

english, 2012

37

CCL5 and CCL20 mediate immigration of Langerhans cells into the epidermis of full thickness human skin equivalents

Krista Ouwehand, Sander W. Spiekstra, Taco Waaijman, Melanie Breetveld, Rik J. Scheper, Tanja D. de Gruijl, Susan Gibbs

Journal:

European Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

38

Preferential Langerhans cell differentiation from CD34+ precursors upon introduction of ABCG2 (BCRP)

van de Ven, Rieneke, Lindenberg, Jelle J, Reurs, Anneke W, Scheper, Rik J, Scheffer, George L, de Gruijl, Tanja D

Journal:

Immunology & Cell Biology

Year:

2012

Language:

english

File:

PDF, 726 KB

english, 2012

39

Dendritic cells in myelodysplastic syndromes: from pathogenesis to immunotherapy

Kerkhoff, Nathalie, Bontkes, Hetty J, Westers, Theresia M, de Gruijl, Tanja D, Kordasti, Shahram, van de Loosdrecht, Arjan A

Journal:

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

40

[Advances in Cancer Research] Applications of viruses for cancer therapy Volume 115 || Adenovirus-Based Immunotherapy of Cancer: Promises to Keep

de Gruijl, Tanja D.

Year:

2012

Language:

english

File:

PDF, 860 KB

english, 2012

41

Targeting the acute myeloid leukemic stem cell compartment by enhancing tumor cell-based vaccines

Ruben, Jurjen M, Visser, Lindy L, Bontkes, Hetty J, Westers, Theresia M, Ossenkoppele, Gert J, de Gruijl, Tanja D, van de Loosdrecht, Arjan A

Journal:

Year:

2013

Language:

english

File:

PDF, 2.95 MB

english, 2013

42

Recent advances in antigen-loaded dendritic cell-based strategies for treatment of minimal residual disease in acute myeloid leukemia

van den Ancker, Willemijn, van Luijn, Marvin M, Westers, Theresia M, Bontkes, Hetty J, Ruben, Jurjen M, de Gruijl, Tanja D, Ossenkoppele, Gert J, van de Loosdrecht, Arjan A

Journal:

Year:

2010

Language:

english

File:

PDF, 4.38 MB

english, 2010

43

Sa1272 Myeloid Derived Suppressor Cell Frequencies Are Increased in Active Refractory Celiac Disease

Gross, Sascha, Nijeboer, Petula, Mulder, Chris J., Bouma, Gerd, von Blomberg, Boudewina M., de Gruijl, Tanja D., Bontkes, Hetty

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 338 KB

english, 2013

44

Applying ceramic nanoporous microneedle arrays as a transport interface in egg plants and an ex-vivo human skin model

Verhoeven, Michel, Bystrova, Svetlana, Winnubst, Louis, Qureshi, Hammad, de Gruijl, Tanja D., Scheper, Rik J., Luttge, Regina

Journal:

Microelectronic Engineering

Year:

2012

Language:

english

File:

PDF, 644 KB

english, 2012

45

Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8 + T-cell cross-priming

Fehres, Cynthia M., Bruijns, Sven C. M., van Beelen, Astrid J., Kalay, Hakan, Ambrosini, Martino, Hooijberg, Erik, Unger, Wendy W. J., de Gruijl, Tanja D., van Kooyk, Yvette

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

46

Allogeneic dendritic cell (DC) vaccination as an “off the shelf” treatment to prevent or delay relapse in elderly acute myeloid leukemia patients: results of Phase I/IIa safety and feasibility study

Tanja de Gruijl,Saskia Santegoeds…

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

47

Bispecific antibody platforms for cancer immunotherapy

Lameris, Roeland, de Bruin, Renée C.G., Schneiders, Famke L., van Bergen en Henegouwen, Paul M.P., Verheul, Henk M.W., de Gruijl, Tanja D., van der Vliet, Hans J.

Journal:

Critical Reviews in Oncology/Hematology

Year:

2014

Language:

english

File:

PDF, 1.64 MB

english, 2014

48

A Single-Component CD40-Targeted Adenovirus Vector Displays Highly Efficient Transduction and Activation of Dendritic Cells in a Human Skin Substrate System

Korokhov, Nikolay, Noureddini, Sam C., Curiel, David T., Santegoets, Saskia J. A. M., Scheper, Rik J., de Gruijl, Tanja D.

Journal:

Molecular Pharmaceutics

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

49

Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: How to break a vicious cycle

Wurdinger, Thomas, Deumelandt, Katrin, van der Vliet, Hans J., Wesseling, Pieter, de Gruijl, Tanja D.

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

50

Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival

De Remigis, Alessandra, de Gruijl, Tanja D., Uram, Jennifer N., Tzou, Schey-Cherng, Iwama, Shintaro, Talor, Monica V., Armstrong, Todd D., Santegoets, Saskia J.A.M., Slovin, Susan F., Zheng, Lei, Lahe

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 568 KB

english, 2015